Posted by on April 02, 19100 at 11:09:03:
In Reply to: Dr. please answer - Metformin Question posted by Susan on April 01, 19100 at 20:44:41:
: Hi! I'm a non-insulin-resistant pcos pt on metformin 500mg tid. I ovulated after 2 months on the med. and had an iui, but no pregnancy resulted. Since then (last 2 months), I have not ovulated (I'm very bad about taking the med. at the correct intervals). QUESTION: Is it reasonable to up the dosage to either 875mg. bid or 1,000mg. bid? I feel that dosing it twice a day will make it easier to stick to a schedule, and perhaps make a difference in cycling. I don't want to approach my r.e. if it's not reasonable or there are no studies to back this approach, especially since I'm not i.r. Thanks in advance for the answer. Sorry so long!
I would suggest that you contact your RE about the difficulties in taking the medications 3x/ day. You are not alone. Studies have shown that less that 65% of people take a medication three times a day for one week the entire course. Imagine if you were to look at compliance for a longer interval. Some do use Metformin twice daily for that reason. Call your RE - it is better that they know what you are doing and not assume what you are doing. Good luck
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