Re: Q for Dr. regarding day 3 estradiol level

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Posted by Serena Chen, MD on August 03, 19100 at 09:57:03:

In Reply to: Q for Dr. regarding day 3 estradiol level posted by Laika on August 02, 19100 at 16:20:06:

Dear Laika:
You are correct. Laboratory results can vary between programs. The meaning of an elevated E2 level is much more controversial than the meaning of an elevated FSH level. We have not found them to be that predictive of prognosis. If we used 80 as a cut-off point, 83 is so close, I would not have enough confidence in the test to exclude someone from attempting IVF. I agree with your physician, I would give you a "Pass" on the CCCT!
Good luck to you,
Serena Chen

: I am 40 years old, healthy, going into my 1st IVF cycle.
: I had a CCCT: Day 3 FSH-8; estradiol-83; Day 10-FSH 9.8.
: My doctor says I passed the CCCT. My question - is
: the estradiol too high? I am reading the clinical
: trials (Cornell and UCLA)that state any estradiol
: level over 75-80 resulted in no pregnancies,
: even with normal FSH levels. I realize that assays
: at different labs may be different - but not sure.
: Just wanted an expert opinion. Thanks so much.

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