Posted by ss on July 28, 19100 at 11:40:29:
In Reply to: Q on aggressive high responder protocols for PGD patient posted by Ellen K. on July 28, 19100 at 09:12:51:
this might have nothing with your eggs or your protocol this problem is very often seen with severe male factor when the sperm count is very low.maybe he tries some vitamins it did help some people bring up there counts. Ask your urologist about it.
Good Luck and Dont Give Up
ss
: The good news is that I produce lots of eggs... the bad news is that not many are mature. This wouldn't be so bad if we didn't lose 70+% of our embryos after PGD:
: IVF#1 - 21 eggs retrieved (only 7 days of stims), 10 fertilized (w/ICSI), 8 biopsied, only 1 embryo remaining after PGD, no pregnancy
: IVF#2 - (high responder protocol - 4 weeks of bcps overlapped with one week of Lupron) - 20 eggs retrieved (only 7 days of stims again), 8 fertilized (w/ICSI), 6 biopsied, again only 1 embryo remaining after PGD, no pregnancy
: Stim protocol each cycle was 2amps Gonal F + 2amps Repronex + 10IU Lupron each day. In each cycle, my e2 after 3 days of stims was very high, so (1) Gonal F was discontinued and (2) I only stimmed for 7 days (peak e2 was >3000). So essentially I triggered before the smaller eggs could fully develop.
: I'd like to know:
: 1) Are there are any other more aggressive high responder protocols available? (I can't help believing that if I could produce a few more mature eggs, we'd have more embryos after PGD)
: 2) I'm only 25, and our fertility problems are due to male factor -- since I respond so quickly to the stims at this age, any speculation on what a few years of waiting would do? Maybe my ovaries won't be so hyperactive at age 30???
: Thanks for your feedback!