Posted by on March 24, 19100 at 13:39:30:
In Reply to: Re: Rezulin posted by Ellen Bender on March 23, 19100 at 14:29:58:
Ellen,
What is d-chiro inositol (or INS-1). Is it an insulin sensitizing agent as well? If not, what does it do?
: Angela: There are two other insulin sensitizing agents that work similarly to Rezulin, but do not appear to carry the same risks of liver damage with them (though patients on these drugs should be monitored carefully to ensure that they do not have any liver problems). The drugs are Actos, marketed by Eli Lilly and Takeda Chemicals and Avandia marketed by SmithKline Beecham. Note, however, that like Metformin and Rezulin (formerly), these medications are FDA approved for type II diabetes but not for PCOS. In addition, as you may know, there is a new medication, called d-chiro inositol (or INS-1) which is in clinical trials and has shown a lot of promise for women with PCOS. It is being developed by Insmed Pharmaceuticals. _ Ellen